<span>he Streptococcus pneumoniae capsule is vital for virulence and may inhibit complement activity and phagocytosis. However, there are only limited data on the mechanisms by which the capsule affects complement and the consequences for S. pneumoniae interactions with phagocytes. Using unencapsulated serotype 2 and 4 S. pneumoniae mutants, we have confirmed that the capsule has several effects on complement activity. The capsule impaired bacterial opsonization with C3b/iC3b by both the alternative and classical complement pathways and also inhibited conversion of C3b bound to the bacterial surface to iC3b. There was increased binding of the classical pathway mediators immunoglobulin G (IgG) and C-reactive protein (CRP) to unencapsulated S. pneumoniae, indicating that the capsule could inhibit classical pathway complement activity by masking antibody recognition of subcapsular antigens, as well as by inhibiting CRP binding. Cleavage of serum IgG by the enzyme IdeS reduced C3b/iC3b deposition on all of the strains, but there were still marked increases in C3b/iC3b deposition on unencapsulated TIGR4 and D39 strains compared to encapsulated strains, suggesting that the capsule inhibits both IgG-mediated and IgG-independent complement activity against S. pneumoniae. Unencapsulated strains were more susceptible to neutrophil phagocytosis after incubation in normal serum, normal serum treated with IdeS, complement-deficient serum, and complement-deficient serum treated with IdeS or in buffer alone, suggesting that the capsule inhibits phagocytosis mediated by FcÎł receptors, complement receptors, and nonopsonic receptors. Overall, these data show that the S. pneumoniae capsule affects multiple aspects of complement- and neutrophil-mediated immunity, resulting in a profound inhibition of opsonophagocytosis.</span>
The archaea are in a different domain from bacteria due to certain differences in their morphology and habitats, the Archaea are the separate domain of life in prokaryotes. For example; unlike bacteria, archaea cell walls do not contain peptidoglycan, they have different membrane lipid bonding from bacteria and eukarya.
Archaea is considered as the different domain of life in prokaryotes, as they are the most primitive type and known as the ancient microbes found in extreme niches such as hydrothermal vents, higher salt concentration, high temperature, and pressure etc
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b.) recycling glass, plastics, and metals <span>would result in the greatest reduction of waste
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Answer:
The correct answer is: Recapitulation Theory.
Explanation:
The Recapitulation Theory began as an idea by Étienne Serres in the 1820s that later, in 1886, was took by Ernst Haekel when he proposed his "<em>Ontogeny recapitulates phylogeny</em>" theory. Recapitulation Theory combines evolution and embryology and states that the development of an individual when an embryo, summarizes the evolutionary history of its species.
