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Answer:
How scientific research uses the internet to get to know living things
Explanation:
Answer:
Principles of Geology
Explanation:
J. Henslow gifted Darwin the first volume of Principles of Geology, written by Charles Lyell. The book explains about the old age of the earth. Accordingly, the slow rate of several geological processes suggests that the earth is very old.
Darwin read the book as the ship was crossing the Atlantic and learned about geological processes occurring over the millions of years. For example, he learned that the earth's surface was not formed by some catastrophic event.
In his book, Lyell explained the slow and gradual geological processes like erosion gave rise to the vast landscapes present on the earth's surface.
Darwin compared the time taken by geological processes to form the earth's surface and reasoned if these millions of years were enough to support the evolution of species.
Answer:
I believe option <u>C. Photosynthesis</u> is correct.
Explanation:
6H20 + 6CO2 + light = C61206+602 is the symbol form of Carbon dioxide + water + light = sugars + oxygen.
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Answer:
Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.