All categories

4 years ago

How can I start for drug design to end up having a career as a drug designer?

Business

1 answer:

MatroZZZ [7]4 years ago

6 0

Answer:

Inorder to start for drug design to end up having a career as a drug designer, one needs to follow the processes below;

1. Discovery

2. Product characterization

3. Formulation, delivery, packaging development

4. Phamacokinetics and drug disposition

5. Preclinical toxicology testing and IND application

6. Bioanalytical testing

7. Clinical trials

Explanation:

Drug design is a method in which one develops new medicinal drugs based on the knowledge of a biological target.

The knowledge of the biological target is it's molecular make up. Once the molecular information about the target has been determined, the drug is developed to compliment the bio-molecular properties of the target.

The bio-molecular properties usually considered are the shape and the charge.

There are seven major processes to complete drug design. They are as follows;

1. Discovery

This starts with a target identification where the biochemical relationship involved in the disease condition. The interaction between a drug candidate and the drug target is determined using rigorous screening processes. A lead compound is chosen after effective review.

2. Product characterization

The candidate molecule is then classified and its characteristics noted.

3. Formulation, delivery, packaging development

Formulations for proper drug delivery parameters should be determined. This will include all parameters of shipment and storage to ensure proper and safe delivery.

4. Phamacokinetics and drug disposition

Pharmacokinetics(Pk) offer useful feedback to the formulation scientists. Pk offers parameters such as area under the curve and the maximum concentration of the drug in the blood and the time at which the maximum concentration is reached.

5. Preclinical toxicology testing and IND application

This involves the testing of the bio-activity, safety and efficacy of the formulated drug product

6. Bioanalytical testing

This is important for proper characterization of the molecule

7. Clinical trials

The clinical trial are conducted by grouping them into three types, majorly;

human pharmacology, therapeutic exploratory, and therapeutic confirmatory

You might be interested in

A growing trend to "Buy American" may encourage U.S. automakers to increase political pressure on Washington to pass legislation

Kazeer [188]

Answer:

C) a positive result from regulatory and economic environmental forces.

Explanation:

In the short run the whole economy will benefit, more American jobs will be created, consumers will probably get good cars at even lower prices, but on the long run the scenario may not be that good for everyone. If Toyota builds the plant, it will be the result of economic and political pressures, and that is a game that two can play, just ask farmers about the trade deal with China.

On the other hand, this is a type of deja vu (or been there, done that), and it ended up with GM and Chrysler bankrupt and Ford barely surviving. This types of policies were enforced in the 1980s by president Reagan and the famous "Made in the USA" by Bruce Springsteen. Back then Honda had a small factory and Toyota was starting to consider building a plant in the US, Nissan hadn't showed up yet. Fast forward a few years and the only good American vehicles are pickups, the Japanese brands wiped out the rest. The country is full of Camrys, Accords, Civics, Corollas, CRVs and Rav4s. They are great cars, too great for the American car manufacturers to compete against. Who knows, with this type of policies maybe in 10 years the only American car manufacturer left will be Tesla.

This is like playing with fire on top of a fuel truck.

5 0

3 years ago

Barry has a medical plan with a $1,200 deductible, 20% coinsurance, and a $5,000 coinsurance cap. His allowable medical expenses

Trava [24]

Based on his deductible and coinsurance cap, the amount that Barry will pay is $4,560.

<h3>Amount Barry will pay </h3>

Barry will have to pay the entire deductible of $1,200. The expenses that are left will then be shared between him and the insurer in a 20% - 80% ratio but he will not pay more than $5,000.

Total he will pay out of pocket is therefore:

= Deductible + ( 20% x (Medical expenses - deductible))

Solving gives:

= 1,200 + ( 20% x (18,000 - 1,200))

= $4,560

In conclusion, he will pay $4,560.

Find out more on insurance payments at brainly.com/question/25973180.

4 0

2 years ago

If the superior's job with a particular employee during a performance appraisal is simply to sit and listen and then have open

igor_vitrenko [27]

I’m not sure about the first one (my best guess is B.) but the second one is A.