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vivado [14]
3 years ago
14

How can I start for drug design to end up having a career as a drug designer?

Business
1 answer:
MatroZZZ [7]3 years ago
6 0

Answer:

Inorder to start for drug design to end up having a career as a drug designer, one needs to follow the processes below;

1. Discovery

2. Product characterization

3. Formulation, delivery, packaging development

4. Phamacokinetics and drug disposition

5. Preclinical toxicology testing and IND application

6. Bioanalytical testing

7. Clinical trials

Explanation:

Drug design is a method in which one develops new medicinal drugs based on the knowledge of a biological target.

The knowledge of the biological target is it's molecular make up. Once the molecular information about the target has been determined, the drug is developed to compliment the bio-molecular properties of the target.

The bio-molecular properties usually considered are the shape and the charge.

There are seven major processes to complete drug design. They are as follows;

<em>1. Discovery</em>

This starts with a target identification where the biochemical relationship involved in the disease condition. The interaction between a drug candidate and the drug target is determined using rigorous screening processes. A lead compound is chosen after effective review.

<em>2. Product characterization</em>

The candidate molecule is then classified and its characteristics noted.

<em>3. Formulation, delivery, packaging development</em>

Formulations for proper drug delivery parameters should be determined. This will include all parameters of shipment and storage to ensure proper and safe delivery.

<em>4. Phamacokinetics and drug disposition</em>

Pharmacokinetics(Pk) offer useful feedback to the formulation scientists. Pk offers parameters such as area under the curve and the maximum concentration of the drug in the blood and the time at which the maximum concentration is reached.

<em>5. Preclinical toxicology testing and IND application</em>

This involves the testing of the bio-activity, safety and efficacy of the formulated drug product

<em>6. Bioanalytical testing</em>

This is important for proper characterization of the molecule

<em>7. Clinical trials</em>

The clinical trial are conducted by grouping them into three types, majorly;

human pharmacology, therapeutic exploratory, and therapeutic confirmatory

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The amount of product available to the market is known as which of the following? Demand Interest Supply Resources
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Answer:

Supply

Explanation: I had to the Economics Cencepts-Assessment ll for DECA today. I got all my answers off a quizlet...

3 0
3 years ago
Imagine you have some workers and some handheld computers that you can use to take inventory at a warehouse. There are diminishi
skad [1K]

Answer:

a. The cost of inventorying a single item is $1.00 per item.

b. The cost of inventorying a single item is $0.86 per item.

c. The cost of inventorying a single item is $0.95 per item.

d. The cost of inventorying a single item is $1.08 per item.

e. You should assign two workers per computer in order to minimize the cost of inventory per single item.

Explanation:

Note: This question is not complete. A complete question is therefore provided before answering the question as follows:

Imagine you have some workers and some handheld computers that you can use to take inventory at a warehouse. There are diminishing returns to taking inventory. If one worker uses one computer, he can inventory 125 items per hour. Two workers sharing a computer can together inventory 175 items per hour. Three workers sharing a computer can together inventory 185 items per hour. And four or more workers sharing a computer can together inventory fewer than 185 items per hour. Computers cost $100 each and you must pay each worker $25 per hour.

a. If you assign one worker per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $ _____ per item

b. If you assign two workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $ _____ per item

c. If you assign three workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $_____ per item

d. If you assign four workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $_____ per item.

e. How many workers per computer should you assign if you wish to minimize the cost of inventory per single item? _____ worker(s) per computer

The explanation to the answer is now provided as follows:

Note: See the attached excel file for all the calculations.

a. If you assign one worker per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $ _____ per item

The cost of inventorying a single item is <u>$1.00 per item.</u>

b. If you assign two workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $ _____ per item

The cost of inventorying a single item is <u>$0.86 per item.</u>

c. If you assign three workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $_____ per item

The cost of inventorying a single item is <u>$0.95 per item.</u>

d. If you assign four workers per computer, what is the cost of inventorying a single item? Instructions: Round your answer to two decimal places. $_____ per item.

The cost of inventorying a single item is <u>$1.08 per item.</u>

e. How many workers per computer should you assign if you wish to minimize the cost of inventory per single item? _____ worker(s) per computer

To minimize the cost of inventory per single item, you should assign the number of workers at a point where the cost inventorying a single item is the lowest.

From from parts a to d above, the <u>lowest cost of $0.86 per item </u>of inventorying a single item is obtained in part b when you assign two workers per computer.

Therefore, you should assign two workers per computer in order to minimize the cost of inventory per single item.

Download xlsx
6 0
3 years ago
A company purchased new equipment for $48,000. The company paid cash for the equipment. Other costs associated with the equipmen
brilliants [131]

Answer:

The cost recorded will be $53,400

Explanation:

In this question, we are to give the value of the amount recorded as the cost of the new equipment.

By simply doing some additions, we will be okay.

mathematically, this would be

Cost of equipment recorded = cost of equipment + transportation cost + sales tax + installation cost = 48,00 + 1,200 + 2,500 + 1,700 = $53,400

4 0
3 years ago
Your grandparents would like to establish a trust fund that will pay you and your heirs $215,000 per year forever with the first
Tju [1.3M]

Answer:

They should invest $5,119,047.619 today.

Explanation:

The trust fund will pay a fixed amount forever thus it is a perpetuity. The value of perpetuity or Price of perpetuity is the amount that the perpetuity is worth in today's terms based on the cash flows it will generate in future.

The formula for the value or price of perpetuity is,

P0 or V = Cash Flow / r

Thus,

P0 or V = 215000 / 0.04   =  $5,119,047.619

7 0
3 years ago
Onslow Co. purchased a used machine for $178,000 cash on January 2. On January 3, Onslow paid $2,840 to wire electricity to the
Aleksandr-060686 [28]

Answer:

First we must determine the total cost of the machine:

total cost = $178,000 + $2,480 + $1,160 = $181,640

Now we must find the depreciable value:

depreciable value = total cost - salvage value = $181,640 - $14,000 = $167,640

since the machine is going to be used for six years, the depreciation expense per year = depreciable value / useful life

depreciation expense per year = $167,640 / 6 years = $27,940

if it was depreciated during 5 years, the total depreciation expense would be: $27,940 per year x 5 years = $139,700

If the machine was depreciated before time, and sold only at its salvage value, Onslow Corp. should report a loss of $27,940.

7 0
3 years ago
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