Lysosomes are membranous organelles that contain digestive enzymes. Lysosomes can function inside the cell, where their enzymes
digest particles taken in by endocytosis or worn‑out cell components. Lysosomes can also release their enzymes outside the cell, where the enzymes break down extracellular material. I‑cell disease is a lysosomal storage disease that results in the buildup of carbohydrates, lipids, and proteins as inclusion bodies within the cell. Which is the probable cause?
I cell disease is caused by a mutation in GNPTA gene that leads to deficiency in the enzyme UDP-N-acetylglucoseamine-1-phosphotransferase.
Explanation:
I cell disease (mucolipidosis) is a rare inherited lysosomal storage disease that results in the buildup of carbohydrates, lipids, and proteins as inclusion bodies within the cell GlcNAc-1-phosphotransferase catalyzes the N-linked glycosylation of asparagine residues with a molecule called mannose-6-phosphate (M6P). M6P acts as an indicator of whether a hydrolase should be transported to the lysosome or not. Once a hydrolase indicates an M6P, it can be transported to a lysosome. Mutation in this gene causes this disease.
Answer – The force of gravity is
stronger than the force of magnetism.
The attractive force of magnetism
is the force that keeps the nails joined to one another and to the end of a bar
magnet while the force of gravity is the force acting to pull the nails to the
ground. If when Juanita sticks the seventh nail, it falls off the sixth nail,
it means that the force of gravity acting on the seventh nail is stronger than
the force of magnetism acting on it.