Many g protein-coupled receptors contain seven transmembrane α-helical domains. the amino end of the protein lies at the exterio
r of the plasma membrane. loops of amino acids connect the helices either at the exterior surface or on the cytosolic surface of the membrane. the loop on the cytosolic side between helices 5 and 6 is usually substantially longer than the others. where would you expect to find the carboxyl end of the protein?
<span><span>The carboxyl end of the G- protein-coupled receptor (GPCR) is located in the cytosol (it is intracellular). Carboxyl terminus is one of the most variable structures of the protein. All of the GPCR are </span><span>structural and functional similar, unlike their ligands.</span></span>
