The FDA seal of approval is NOT a source to ensure quality of a dietary supplement. The answer to your question is C. I hope this is the answer that you are looking for and it comes to your help.
A diagnosis is the name or identification of a problem according to ones symptoms
Molecules that cannot cross the membrane bind to receptors in the membrane. When the signal binds to a receptor changes it's shape. Other Molecules inside the cell respond to the chainging shape of the receptor.
Chromosome non-disjunction, anaphase lag and endoreplication