Answer:
Positive Trousseau sign
Positive Chvostek sign
Hyperactive reflexes.
Muscle twitching, Paresthesias
When the blood conce
Explanation:
When the blood ca+ concentration falls below the standard of 4.4-4.5mg/dL,that is below 4.4mg/dL the clinical condition is called hypocalcemia. It is caused by hypothyroidism,due to malfunction of the parathyroid gland.
Generally, Ca+ is needed for contraction of muscles by causing the fusion of the vesicles containing neurotransmitters to the presynaptic membrane for the passage of neuro transmitters to fuse with the receptors on the sarcolemma to initiate muscular contractions by opening of ligand gated Na+. It also interact with the ligand gated sodium ion channels
Generally,Ca+ inhibits depolarization of ligand gated Na+ channels. Thus blocks the opening of these channels and therefore the rate of excitability.Therefore, If the is low serum levels of Ca+,There is increased in the threshold of depolarization because more ligand gated Na+ channels are opened,Thus their is increased excitability of nerves and muscles fibres therefore in the clinical manifestations listed above.
It can be treated with infusion of Ca+ into the blood.
