It would be the endocrine system.
The time period being referred to is the sensitive period. This time period is also referred to as the critical period. The importance of a critical period is such that it must involve certain stimuli from which an organisms learns and acquires traits. If some of these stimuli are not present in the critical period, the organism has difficulty acquiring the trait or skill, and may even find it to be impossible to learn the skill.
Hypertension (high blood pressure) has negative effects on health because people with this condition have a higher risk for heart disease and other medical problems than people with normal blood pressure.
If left untreated , hypertension can lead to :
1. heart attack
2. Stroke
3. enlarged heart
4. Kidney damage.
Once the kidneys are damaged, homeostasis in the body is severely impaired because the body no longer has the ability to clear waste products, which when they accumulate tend to poison the body leading to such conditions as uremia.