As "nurse" cells for neurons in the brain parenchyma, astrocytes are resident glial cells produced from neuroectoderm.
How astrocytes become pathological?
- Recent research has identified astrocytes as major disease-propagating agents in mutant human superoxide dismutase 1 (mSOD1)-mediated amyotrophic lateral sclerosis (ALS).
- However, due to the widespread expression of mSOD1 throughout the CNS of the investigated rodent models, in vivo examination of a specific astrocytic effect in amyotrophic lateral sclerosis has proven challenging.
- In order to understand how mutant astrocytes affect WT MNs and other cell types (microglia and astrocytes) in an in vivo environment, we transplanted SOD1(G93A) glial-restricted precursor cells into the cervical spinal cord of WT rats.
- SOD1(G93A) glial-restricted progenitor cells that were transplanted survived and successfully differentiated into astrocytes.
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Hey! I think the correct answer would be the last one! Estuaries are where fresh water from rivers and streams mixed with salt water
Answer:
Centripetal Force Vs Centrifugal Force.
Explanation: