Answer:
The shape of the abnormal red blood cells in sickle cell anemia can affect the efficiency of the circulatory system by obstructing the flow of blood through the arteries.
Explanation:
Red blood cells are the cells responsible for transporting oxygen and carbon dioxide throughout the body, and their spherical shape allows them to pass through blood vessels of any calibre.
<u>A red blood cell in sickle cell disease loses its spherical shape</u>, acquiring a half-moon shape, which can lead to its accumulation inside the arteries and produce a blockage, <u>decreasing the efficiency of the circulatory system</u>.
The arterial obstruction may lead to a decrease in oxygenation in the sites that are irrigated by that artery.
Learn more:
Sickle cell anemia brainly.com/question/900881