Answer:
Heterotroph. Autotrophs are organisms that can produce their own food from the substances available in their surroundings using light (photosynthesis) or chemical energy (chemosynthesis). Heterotrophs cannot synthesize their own food and rely on other organisms — both plants and animals — for nutrition.
Explanation:
Heterotroph. Autotrophs are organisms that can produce their own food from the substances available in their surroundings using light (photosynthesis) or chemical energy (chemosynthesis). Heterotrophs cannot synthesize their own food and rely on other organisms — both plants and animals — for nutrition.
Yes, it is true that Methylation of EZH2 by PRMT1 regulates its stability and promotes breast cancer metastasis.
Enhancer of zeste homolog 2 (EZH2), a key histone methyltransferase and EMT inducer, is overexpressed in diverse carcinomas, including breast cancer.
However, the molecular mechanisms of EZH2 dysregulation in cancers are still largely unknown. Here, we discover that EZH2 is asymmetrically dimethylated at R342 (meR342-EZH2) by PRMT1.
meR342-EZH2 was found to inhibit the CDK1-mediated phosphorylation of EZH2 at T345 and T487, thereby attenuating EZH2 ubiquitylation mediated by the E3 ligase TRAF6.
We also demonstrate that meR342-EZH2 resulted in a decrease in EZH2 target gene expression, but an increase in breast cancer cell EMT, invasion and metastasis.
Moreover, we confirm the positive correlations among PRMT1, meR342-EZH2 and EZH2 expression in the breast cancer tissues. Finally, we report that high expression levels of meR342-EZH2 predict a poor clinical outcome in breast cancer patients.
Our findings may provide a novel diagnostic target and promising therapeutic target for breast cancer metastasis.
Learn more about breast cancer here : brainly.com/question/6747562
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Plants release oxygen into the atmosphere during photosynthesis while respiration by plants and animals and the decomposition and decay of dead organisms releases carbon dioxide into the atmosphere. These three produce maintain a cycle in which plants and animals depend on and benefit from each other.
I think it would be B, please let me know if that's wrong!
Beacuse they died long time ago
