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Answer:
Humans have nearly 30,000 genes that determine traits from eye color to risk for hereditary diseases. Those genes sit along six feet of DNA, which are organized into chromosomes and stuffed into each and every human cell. Chromosomes are coiled into loops and then organized into many large domains called topologically associating domains (TADs).
Explanation:
Answer:
The best answer to the question: If every gene has a tissue-specific and signal-dependent transcription pattern, how can such a small number of transcriptional regulatory proteins generate a much larger set of transcriptional patterns? Would be:
Because transcriptional regulators, which are the ones responsible for initiating, and stopping, transcription of RNA into protein, often work in pairs, one goes with the other, and thus increase the regulatory capabilities over gene expression so that the genes translated into RNA and then transcribed into aminoacids in protein chains, actually code for the correct protein types.
These regulators will both stand, as appropriate, on a specific gene to promote its transcription, or prevent it, depending on the different signaling mechanisms received.
