In spherocytosis, there is a defect in the membrane proteins of the red blood cells, specifically ankyrin and spectrin. These membrane proteins contribute to the biconcave shape of red blood cells therefore the loss of these proteins will lead the red blood cells to lose its biconcave shape--leading to abnormally shaped red blood cells (spheres) hence the name. This can lead to premature destruction of red blood cells and jaundice due to hyperbilirubinemia. Spherocytes do not hold oxygen and carbon dioxide well as spherocytes have a decreased surface area.
Answer:
Hemoglobin is responsible for binding and transporting oxygen in the body. It is a tetrameric protein that is found in high concentration in red blood cells (erythrocytes, red blood cells). Each hemoglobin molecule is made up of four subunits: two of the alpha type and two of the beta type, and each subunit can bind an oxygen molecule through its heme group.
Structure studies have shown that hemoglobin can adopt two conformations, called T (tense) and R (relaxed). Deoxyhemoglobin (in blue) is in state T, and the union of oxygen (in red) causes the transition to state R. The animation shows a close view of the heme group (in white, balls and rods) of one of the subunits of hemoglobin. In the deoxygenated state (T), the iron atom is not coplanar with the rest of the heme group due to its association with the histidine side chain. The union of oxygen displaces the iron atom so that it remains coplanar with the rest of the heme group, which in turn drags histidine, producing a larger-scale conformational change that affects the entire protein.
Hemoglobin can be considered as a tetramer formed by two alpha-beta dimers. The conformational change associated with the transition from T to R mainly affects the relative position of these two dimers (rather than the interactions between the alpha and beta subunits within a dimer). This is illustrated in the last stretch of the animation (drawn in black and white).
Mythology. When Zeus fell in love with the Phoenician Princess Europa, he transformed himself into a white bull with golden horns named Taurus and carried Europa away to Crete. Taurus, located between the constellations Aries and Gemini, is referenced in astrology, which is not a science
An organelle is a specialized structure inside Eukaryotic cells.
I think it's in Antarctica. The frozen water :/
