Answer:
Hope this is helpful! Sorry if my answer is choppy.
Explanation:
Biotic and abiotic features are both important in ecosystems because for example, a biotic factor like a plant, relies on an abiotic factors like the rain and the sun. If the rain were non existent, then the plants would no longer be alive causing a chain reaction in the food system. Biotic factors like plants and animals that are non existent can also cause negative effects in biomes and ecosystems.
Answer:
Polar
Explanation:
A water molecule, because of its shape, is a polar molecule. That is, it has one side that is positively charged and one side that is negatively charged. The molecule is made up of two hydrogen atoms and one oxygen atom. The bonds between the atoms are called covalent bonds, because the atoms share electrons. The hydrogen atoms have one electron each.
Human monoclonal antibody (mAbs) are emerging in the field of cancer therapy and have become an increasing proportion of new drugs that are recently approved. Although there are some methods to obtain antigen-specific mAbs from human B cells, it is generally impossible to directly immunize human beings with antigens of interest. For example, for infectious agents, those approaches are largely restricted. To solve these obstacles, two main approaches have been developed; either by humanizing antigen-specific antibodies from small experimental animals (which is laborious due to the great genetic differences from humans) or rely on the in vitro selection of antigen-specific binders from human antibody repertoires. However, the human mAbs developed by these methods are usually with low affinity.
We are now coming up with a much better idea that is humanizing non-human primates mAbs instead of murine mAbs. Due to the close genetic relationship with humans, immunized NHPs have more potential to be isolated with high affinity antibody to human target than other experimental species, such as mouse, rat and rabbit. In addition, with appropriate method, NHP antibodies are much<span> easier to be humanized</span> without any loss of affinity compared to widely used murine antibodies.
Resource: http://www.creative-biolabs.com/High-Affi-TM-Human-Antibody-Discovery.html
Answer:
2, 6 are the one you should select
Explanation: