Question

"compare and contrast the pathogenicity of clostridium botulinum and clostridium tetani, including mechanisms of action of their toxins and disease manifestations."

Answer 1

The two bacteria are considered to be anaerobic endospore-formers that deliver neurotoxins. Disease comes about when the endospores are brought profound into the tissues. The two neurotoxins meddle with engine control. Botulism poison, delivered by C. botulinum, ties the cytoplasmic films of engine neurons at the neurotransmitter and keeps the arrival of acetylcholine neurotransmitter and, subsequently, forestalls motioning to muscle cells. At the point when muscle cells don't get signals from engine neurons, they stay loose, bringing about a flabby loss of motion. The absence of engine control delivers a not insignificant rundown of side effects, the most genuine of which is a respiratory disappointment, on the grounds that respiratory muscles can be influenced by botulism poison.