Generally hormones of the hypothalamus(e.g gonadotropin -releasing hormones,growth hormone-releasing hormone) do not enter general circulation before reaching the ant. pituitary gland. Rather their transport and material exchange from the hypothalamus to the ant. pituitary gland is shunted by network of blood capillaries, in the connective structure that directly linked the hypothalamus with the ant. pituitary.
These network of blood capillaries which pass through the infundibulum at the base of the fore brain is called the hypothalamic-hypophyseal tract. it clinical significance in diseases spread is that it may serve as the route of metastasis from hypothalamus to reach the pituitary.
Anatomically the Infundibulum or pituitary stalk functions in maintaining balance in body water and electrolyte levels of the body and also carry out some endocrine functions by allowing the transport of hypothalamic hormones( e,g ADH, oxytocin to reach the post. pituitary gland
Explanation: The hypothalamus and the pituitary gland (hypophysis) are linked by a structure called the infundibulum. The infundibulum contains vasculature and nerve axons, these nerve axons have endocrine properties.
The hypothalamic-hypophyseal tract runs through this infundibulum
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