C.) it reduced coast to coast communication from about 180 days to about a week
Pennsylvania was developed by William Penn to be a place of freedom of religion.
Thanks to the fact that Mesopotamia was between two major rivers, Tigris and Euphrates, it was possible for agriculture to become highly developed there because the soil was extremely fertile, which led to the rise of the civilizations there.
The Nile River shows the farthest extant of Alexander's Conquests.
Hope I helped. :)
D is the correct answer my friend