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3 years ago

How do genetic/genomic issues influence individual variation of the response to a specific drug

Biology

2 answers:

kari74 [83]3 years ago

6 0

Polymorphicisms of genes encoding metabolizing enzymes

IceJOKER [234]3 years ago

5 0

Answer:

Polymorphism of the gene of metabolizing enzymes.

Explanation:

Polymorphism may be defined as the phenomena of occurence of the same genetic material in the different forms.The multiple forms of the single gene is known as gene polymorphism.

The single nucleotide polymorphism shows the genetic polymorphism. The individuals has the different affect against the same drug. This mainly occur due to the polymorphism or multiple forms of the allele of the same gene that metabolize the drugs.

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Key points: Cells have a variety of mechanisms to prevent mutations, or permanent changes in DNA sequence. During DNA synthesis,

MrMuchimi

Answer:

Explanation:

The above mentioned key points are mechanisms by which cells used to correct replication error and repair damaged DNA.

Proof Reading: while printing a page, the typesetter set the types and impression is taken, proof reading is done to correct mistakes if any, and the final printing is done. A similar follow up mechanism is done after DNA synthesis. If DNA polymerase detects an incorrect nucleotide pair, it will remove and replace with the correct nucleotide immediately.

Mismatch Repair:even after DNA synthesis, mismatch area(insertion or deletion) can be identified on the newly synthesized DNA.

In the mismatch repair, specific proteins scan the newly synthesized DNA strand. The mismatch area is identified and loop.

The second protein complex remove the mismatch segment. Finally correct segment is synthesized by the help of DNA polymerase, SSBs and ligase.

DNA damage repair mechanism: when DNA get damaged, there's a repair process that fix the damage. This includes Direct reversal, excision repair and Double stranded break repair

4 0

3 years ago

Are NAD+ and H+ the same? Or what is the difference between them? Thanks.

Greeley [361]

NAD+ and H+ are not the same.

NAD+ is an electron carrier. Reactions in metabolism oxidize food molecules and transfer those electrons (along with H+) to > NAD+ which is what forms NADH. Now, NADH is the reduced form of NAD+ and NAD+ is the oxidized form of NADH.

H+ on the other hand, is a proton. It is a hydrogen atom that lost it's electrons. So when you see NADH + H+, that means that the reaction removed 2 electrons and 2 H+ from the compound.

7 0

3 years ago

Which of the following choices correctly shows the way energy flows in an ecosystem?

AlladinOne [14]

A. Bacteria to Seaweed to Fish to Seal to Polar Bear

5 0

2 years ago

_______ is a major mineral important for nerve and heart function and is a cofactor for over 300 enzymes. it is a major constitu

Ksju [112]

Magnesium is the major mineral which is important for nerve and heart functions. It is a co-factor for over 300 enzymes. It is a major constituent of bone and is found in whole grains and vegetables. Sudden heart attacks may be due to the low level of magnesium. It can be obtained by consuming rice bran, sunflower seed, wheat barn and linseed meal.

5 0

4 years ago

Where is the friction that allows the skater to complete the move that is occurring in this image?

prohojiy [21]

<h2 /><h2> $\huge\colorbox{Orange}{QUESTION AND ANSWER}$ </h2>

Where is the friction that allows the skater to complete the move that is occurring in this image?

D. The point of contact between the skates and her foot.

<h2>KAntoneDoix (^_^)</h2>

6 0

3 years ago