<h2>Alice's daughter Alix =X X* </h2><h2>George V= XY </h2><h2>Progeny are;</h2><h2>XX, XY, X*X, X*Y </h2><h2>50 % males would be infected </h2><h2>50% male normal</h2><h2>50% female normal, </h2><h2>50 female carrier. </h2>

Explanation:

Hemophilia is an inherited disease and it follows an X-linked recessive pattern. The genes for hemophilia disease are located on the X chromosome. In males one mutated copy of the chromosome X is sufficient to cause the condition, because male contain only one gene. Female contain XX chromosome, so both the chromosome must have mutated for causing this disease.

According to study of Queen Victoria (1891-1901) of England, Alice's daughter Alix was X linked carrier and George V was normal male,

so if they got married, their children would be

parents genotype X X* XY

progeny

XX, XY, X*X, X*Y

50% males would be infected

50% male normal

50% female normal,

50 female carrier.

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3 years ago