It depends on the concentration of nerve receptors in different areas of the skin.
Answer:
The molecule on the right; the middle carbon is asymmetric
Explanation:
Numerous degenerative neurological conditions, most notably Parkinson's disease, have been linked to an excessive buildup of alpha synuclein (a-syn) in the brain. Intraneuronal inclusions, often known as Lewy bodies, are neuropathological characteristics seen in Parkinson's disease, Lewy body dementia, and other synucleopathies. The aggregation of a-syn is their main structural component. A-syn accumulation, aggregation, and ensuing Lewy body formation can be attributed to a variety of biological processes. These include genetic changes in parkin, synuclein, or the deubiquitinating enzyme ubiquitin C-terminal hydrolase (UCH-L1), which results in less efficient removal of a-syn via the ubiquitin proteasomal pathway (UPP). Additionally, environmental variables and an age-related decline in antioxidant defense mechanisms that heighten oxidative stress and can have an impact on the formation or clearance of a-syn are intracellular insults.
We focused on changes in the aggregation and clearance of a-syn as impacted by the UPP and the oxidative stress pathways in our dynamic models of a-syn processing in both normal and various disease states. A free radical profile similar to that observed in vivo after exposure to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine is produced during simulation of enhanced oxidative stress (MPTP). To replicate the kinetics of a-syn that correlates to the neuropathology reported for the sporadic and hereditary types of Parkinson's disease, different model parameters of oxidative stress, UPP failure, or both routes are used. With the use of this in silico model, it is possible to evaluate the kinetics of pathway elements and more accurately identify and validate key pharmaceutical targets.
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Oparin and Haldane's theory and Miller's experiment are the proof that long complex molecules that carry information such as DNA, might have formed on early earth.
Explanation:
Oparin and Haldane Hypothesis states that life on Early earth could have evolved by chemical evolution.
Oparin and Haldane said that the reducing atmosphere of the early earth caused simple inorganic molecules to react by using sunlight and formed molecules like amino acids and nucleotides.
These monomers combined to form polymers, they would have attained self-replicating tendency eventually these would have assembled into structures and these macromolecules had also made membrane-bound organelle.
Although this hypothesis is not fully accepted but part of it which talks about formation of molecules is accepted.
Millers and Urey in their experiment created an artificial reducing environment like that of early earth. They used a heated pool of water, atmospheric gases like H2O,CH4,N2, NH4 and sparks of electricity. After running the experiment for some days they found that amino acids, sugars, lipids and other organic molecules had formed.
Their hypothesis is not fully accepted but part of is evident that organic building block is formed from inorganic constituent on the earth.
Answer:
84
Explanation:
42 X 2 since it is a pair
