A coefficient is a number that is being multiplied by a variable. In this case, we see that x in one term is being multiplied by 4, and in another term, x is being multiplied by -16 (If you change the operation to addition, you negate the 16).
So the coefficients in this expression are: 4 and -16.
First, i put the equation in y=mx+b by dividing 2, since its 2y. since it’s perpendicular we’re talking about you switch the sides (opposite reciprocals). the rest should be self explanatory.