Joint hypermobility syndrome (JHS) and Ehlers-Danlos syndrome, hypermobility type (EDS-HT) are the tissue disorders which can be characterized by chronic pain, joint instability complications, and minor skin changes. During these, Fatigue and headache are the very common symptoms; though they can be diagnosed using specific criteria.
JHS/EDS-HT is a rare common condition that could not be diagnosed by most clinicians and pain specialists, resulting in interventions like symptomatic and non-satisfactory treatments, because there is a lack of reasonable pathophysiologic rationale.
Pain, fatigue, and headache in JHS/EDS are usually treated with the help of certain symptoms or on the basis of doctors’ experience.
<span>Therefore, in order to the cure of such symptoms, doctors suggest pathogenic mechanisms. The major aim of the re-writing of the natural history of JHS/EDS-HT is to raise awareness among clinical geneticists and specialists treating chronic pain conditions about pain and other complications of JHS/EDS-HT.</span>
