Benign is harmless, malignant is dangerous.
<span>achieve a therapeutic objective (cure disease, mitigate symptoms etc.)
minimize toxicity
minimize difficulty of administration
identify dosing regimens</span>List the goals of drug therapytherapeutic window/rangethe plasma concentration range that is effective and safe in treating specific diseasestrue(T,F): The therapeutic response is dependent on drug achieving an adequate plasma concentrationmultiple doses________ are given to stay in the therapeutic windowvolume of distribution (V)<span>an important indicator of the extent of drug distribution into body fluids and tissues
relates the amount of drug in the body to the measured concentration in the plasma
it is the volume required to account for all of the drug in the body if the concentration in all tissues is the same as the plasma tissue.</span>clearancethe process of removing a drug from plasma (expressed as volume of plasma per a given unit of time)true(T,F): Clearance indicates the volume of plasma (or blood) from which the drug is completely removed, or cleared, in a given time period.half-life<span>volume of distribution and clearance influences the _______ of a drug.
Dosing regimen: How often?</span>oral bioavailability<span>clearance and absorption influences the ________ of a drug
Dosing regimen: How much?</span>steady statethe amount of drug administered is equal to the amount of drug eliminated within one dosing interval resulting in a plateau or constant serum drug levelshortDrugs with a _____ half-life reach steady state rapidlylongDrugs with a ____ half-life take days to weeks to reach steady statetherapeutic windowA steady state is desired within the _________half-lifethe time necessary for the concentration of drug in the plasma to decrease by one-half (50%)about 5How many half-lives are required to reach steady state?loading dosesoften administered at the initiation of an infusion to achieve an immediate therapeutic plasma concentration of the drug (allows rapid achievement of therapeutic serum)true(T,F): The same loading dose is used regardless of metabolism/elimination dysfunction
Answer:
urine, nails, hair
Explanation:
Hair - Is a special matrix for the retrospective investigation of chronic drug abuse or poisoning in criminal cases and allows to demonstrate with sensitive methods even a single administration in low amount.
Urine - Is a preferred sample as it is easy to procure for forensic findings. Drugs and drug metabolites can be the target chemicals for the findings of the forensic explorations in different modes of deaths.
Nails - Using keratinized samples has several advantages over methodologies employing body fluids. Long term exposures to different drugs result in the accumulation of the same in these structures. Nails have been shown to accumulate drugs following a long duration of drug intake. Finger and toenails can accumulate drugs during long term exposure
Answer:
Aerobic Fitness or Cardiorespiratory Endurance - the ability to deliver oxygen and nutrients to tissues, and to remove wastes, over sustained periods of time.
Any activity you do from taking a walk to washing the dishes it requires oxygen.
Regular aerobic fitness exercise increases your body's ability to use oxygen. How well you use oxygen is termed your "aerobic capacity." When your aerobic capacity is high, your heart, lungs and blood vessels efficiently transport and deliver large amounts of oxygen throughout your body. Aerobic exercise helps you in your daily activities.
Explanation:
in other words they are related
hope i helped
Um, isn't it obvious? Get new shoes, duh.
