Question

Replication of the lagging strand of dna is accomplished by repeatedly making __________ followed by 1

Answer 1

Answer:

The correct answer is "short RNA primers; Okazaki fragments".

Explanation:

The missing information of this question is as follows:

"Replication of the lagging strand of dna is accomplished by repeatedly making __________ followed by 1,000-2,000 nucleotide segments called __________"

The correct answer is "short RNA primers; Okazaki fragments".

DNA replication always occurs from 5' to the 3' end, in what is known as the directionality or the end-to-end chemical orientation in molecular biology. This fact makes difficult the synthesis of the lagging strand of DNA. In order to achieve this short RNA primers are bound to  segments of DNA (serving as the 5' end available for the DNA polymerase to synthesize), which leads to the discontinuous synthesis of Okazaki fragments that are later linked together by the enzyme DNA ligase.