Answer:
Intracellular cargo is basically the different molecules that need to be transported within the cell and between the different organelles that form this cell. Most commonly, that cargo is formed by proteins. For these proteins to be formed, three different structures must come into play: the nucleus with its genetic material, the ER (endoplasmic reticulum) and the Golgi apparatus, where the process will be refined.
In order for this transportation, and translocation of cargo to happen, molecules like proteins must first be loaded into vesicles, membrane surrounded sacks that are produced by the ER, and which will ensure that these molecules reach their destination and connect with the correct site where they are supposed to go.
Aside from these transport vesicles, the cell counts with another structural component that will further ensure the correct movement of vesicles, and their cargo, to their correct destination; these are called microtubules and the cytoskeleton. Basically, these microtubules and cytoskeleton are strings of protein chains that extend around the cytoplasm and provide both a roadway for vesicles to move, and also structural support to the entire cell. They are also central during cellular division.