There were many things that made the journey/topic of colonization difficult. There was a drought that prevented crops from growing to their fullest. Do to this drought that also made finding/seeking fresh water difficult for the colonists. The main result of the drought however, led to starvation and the drinking of contaminated and bacterial water. Not only the drought, but some colonies went a long a swampy area which led to mosquitoes. The mosquitoes then passed on deadly diseases to the colonists.
Hopes this helps, my dearest apologizes if I had ANY grammar mistakes! These are just the main difficulties of colonization.
