Question

All strains of human papillomavirus (HPV) are capable of integrating their double-stranded DNA viral genome into host basal cells while waiting for keratinocyte differentiation before initiating viral replication for virion shedding. As a consequence of the integrated genome, HPV strains that more readily transform host cells are more likely to cause an increased expression of viral ________.a. tumor suppressor genes.
b. oncogenes.
c. lytic genes.
d. lysogeny genes.

Answer 1

Answer:

Option B, Oncogenes

Explanation:

Human papillomavirus (HPV) is a virus that has double stranded DNA and it also has a tendency of entering into the cytoplasm of the host cell without un-coating itself.  Since it is a virus, it replicates with in the nucleus of the host DNA polymerase until the basal cells differentiate into keratinocytes. Keratinocytes are keratin producing epidermal cells which hinders the transmission of HPV hence its shedding its essential for transmission of HPV into new host. Over-shedding leads to abnormal expression of HPV  due to change in normal expression pattern.  

Hence, option B is correct