Answer:
The enzyme Topoisomerase functions to prevent super-coiling of the DNA molecule during replication.
Explanation:
- During replication, topoisomerases are required to relieve the positive supercoiling that arises from DNA unwiding mediated by Helicases.
- A DNA topoisomerase is a nuclease that breaks a phosphodiester bond in a DNA strand.
- All topoiomereases are classified as Topoisomerase I and Topoisomerase II depending on whether they cleave one or two strands respectively.
- Topoisomerase I do not use ATP as a source of energy, the reaction is powered by energy stored in super-coiled DNA.
- Topoisomerase II also do not require external energy but it utilizes ATP hydrolysis to drive conformation changes in the protein during reaction cycle.
B. Weighing , because all its checking is the weight.
Answer:
Mutations are essential for evolution to occur because they increase genetic variation and the potential for individuals to differ. The majority of mutations are neutral in their effects on the organisms in which they occur. Beneficial mutations may become more common through natural selection.
