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Anni [7]
4 years ago
9

Proton-pump inhibitors are drugs that block the secretions of gastric acids. Which cells are affected by these drugs?

Medicine
1 answer:
Mashutka [201]4 years ago
4 0

Answer: Parietal cells

Explanation:

Parietal cells secrete hydrochloric acid in the stomach. They are also known as oxyntic cells. They are the epithelial cells which is located in the gastric glands found in the lining of the fundus and cardia of the stomach.

The proton pump blocks the hydrogen ion pump in the parietal cells. These drugs are commonly known by the name of omeprazole.

They block the the H+/K+ ATPase proton pump which inturn inhibits both basal and stimulated secretion of the gastric acid from the cells.

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Answer:

4 tablets t.i.d. (Three times a day)

Explanation:

By use of Dimensional Analysis, you can figure this out:

First, find how many mg she will take in a day:

(132 lbs)(\frac{0.454 kg}{1 lbs})=59.9 kg\\(59.9 kg)(\frac{70 mg}{1 kg} )=4,195mg\\

Since she will take 3 equal doses, divide this by 3:

\frac{4,195 mg}{3} =1398\text{ mg dose}

To find the # of tablets per dose, divide dose in mg by mg per tablet:

(\frac{1398 mg}{dose})(\frac{1 tablet}{350 mg} )=3.995\frac{tablets}{dose}

Since you can't realistically take .995 of a tablet, round up to 4.

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