I believe the answer is the Industrial Revolution
World War I certainly influenced the opinion of Americans about many aspects of the future. The U.S for instance begun to isolate itself from the world and became increasingly unwilling to interfere in any external disputes. However, it also accelerated economic growth and changed attitudes on issues like the rights of women.
Locke is referring to slavery, specifically claiming that it isn't fair to own or dominate anyone else.
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b.) The diverse geography of the colonies encouraged different economic pursuits.
The British colonies contained diverse geography from rocky coast line, forests, hot and humid areas, swamp lands, and good soiled farm land.
The diversity of geography created differing economies for the Thirteen Colonies. New England focused on shipbuilding, lumber, fishing, whaling, manufacturing, trade, and small farming. The Middle Colonies were best for farming for food production. These colonies established farms for what, rye, corn, vegetable, and animal farming. The Southern Colonies were the harshest of environments being hot and humid with swampy land. However, the geography proved perfect for tobacco, rice, sugar, and eventually cotton. The Southern Colonies focused on plantation farming of cash crops and would demand large amounts of labor. The need for labor would be filled by a system of slavery.