The answer is,
d<span>istal convoluted tubule (dst)</span>
The hypothesis by Coleman was that the product of the ob+ gene was the appetite suppressing hormone. Hence, the homozygous ob/ob mutant are in a position to synthesize that hormone, and its circulating level would be zero. He also hypothesized that the product of the db+ gene was the receptor for the appetite-suppressing hormone. Thus, the homozygous db/db mutant would be able to synthesize the hormone but would not be in a position to respond to it. It would eat excessively and produce large amounts of body fat, which in turn would produce large amounts of appetite-suppressing hormone . In the absence of a receptor, the db/db mutant's hormone level would remain abnormally high.
Coleman's hypothesis were confirmed when the precise functions of the ob+ and db+ genes were determined. The peptide hormone encoded by the ob+ gene was named Leptin.
Answer:
The organelle that conduct respiration for the cell is MITOCHONDRIA.
Explanation:
The cells of living organisms are made up of different organelles, each of the organelles have specific functions, which they perform. The mitochondria is the cell organelle that is responsible for carrying out respiration in the cells. Respiration involves the breaking down of glucose molecules in order to produce energy in form of ATP. Mitochondria is also called the power house of the cell because of its function of energy production.