Answer: G protein coupled receptors signalling is terminated by phosphorylation of receptors by cyclic adenosine monophosphate activated protein kinase which blocks the interaction with G protein.
Explanation:
G protein coupled receptors (GPCR) signalling constitute a large protein family that detect molecules outside the cell and signal transduction internally and allow responses. They are majorly found in eukaryotes like yeast . The signalling of GPCR by G protein is terminated by phosphorylation of active receptor by GCPR kinases and protein kinase and also the binding of arrestin proteins.
