Question

Single nucleotide polymorphisms (SNPs) are useful in epidemiology because:

Answer 1

Answer:

b. Their presence is evidence of a defect in DNA replication, and therefore proof that a given disease is present

Explanation:

Single nucleotide polymorphisms (SNPs) result from point mutations and correspond to the position where there is alternation of nucleotides A, C, G, T at a minimum allele frequency of 1% in a given population. SNPs can be present in both coding and non-coding regions of the genome. As a nucleotide alternation is the result of a defect in DNA replication and these defects cause syndromes and diseases; we can say that single nucleotide polymorphisms are evidence of a defect in DNA replication and therefore proof that a particular disease is present.