Adenylate cyclases (ACs) are the membrane-bound glycoproteins that convert ATP to cAMP and pyrophosphate.
When activated by G-protein Gs, adenylate cyclases (ACs), which are membrane-bound glycoproteins, catalyze the synthesis of cAMP from ATP.
Different AC isoforms are widely expressed in various tissues that participate in regulatory systems in response to particular stimuli.
Humans have 9 different AC isoforms, with AC5 and AC6 thought to be particularly important for cardiac activities.
Nitric oxide has an impact on the activity of AC6, hence the protein's nitrosylation may control how it works. However, little is known about the structural variables that affect nitrosylation in ACs and how they relate to G's.
We predict the cysteines that are prone to nitrosylation using this 3D model, and we use virtual ligand screening to find potential new AC6 ligands.
According to our model, the AC-Gs interface's Cys174 in G's and Cys1004 in AC6 (subunit C2) are two potential residues that could experience reversible nitrosylation.
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Answer: The answer is D.
Explanation: Because earthquakes take place in both the Convergent Plate in Location A and Transform Plate in Location B.
Answer:
The digestive system!
Explanation:
The digestive system is made up of the digestive tract - a series of hollow organs joined in a long, twisting tube from the mouth to the anus - and other organs that help the body break down and absorb food.
Organs that make up the digestive tract are the mouth, esophagus, stomach, small intestine, large intestine - also called the colon - rectum, and anus.
The two biggest reasons for children spending less time outside are the development of technology and the safety issues. The development of technology brought in our homes countless forms of having fun which is very important to children. The mobile phones, PC's, laptop's, tablets, Sony Play Station, as well as lots of technologically improved toys, made the children stay at home since they have the fun indoors, and not be interested in going outside and in nature. Also the safety issues in lots of parts in the world made the parents to restrict the children to the indoors environment.
Answer: nucleic acids
Explanation: Among biomolecules, nucleic acids, namely DNA and RNA, have the unique function of storing an organism's genetic code—the sequence of nucleotides that determines the amino acid sequence of proteins, which are of critical importance to life on Earth.
