<span><span>The carboxyl end of the G- protein-coupled receptor (GPCR) is located in the cytosol (it is intracellular). Carboxyl terminus is one of the most variable structures of the protein. All of the GPCR are </span><span>structural and functional similar, unlike their ligands.</span></span>
It can be possible because the mother can present B blood phenotype. This opens the possibility of she having an heterozygous genotype of I^b i or I^b I^b which are dominant over the genotype of the O type father.