An artery ______________________.
c. usually (but not always) carries oxygen-rich blood
Plowing with machines, irrigating with drip systems, and these are all modern agricultural methods.
Fern spore germinates into prothallus.
Explanation:
Ferns are members of phylum pteridophyta, the vascular cryptogams.
These are first land plants which are known to have a distinct conducting system of xylem and phloem.
They reproduce by forming spores that germinates into a heart shaped gametophyte.
The gametophyte of the fern is called prothallus.
The heart shaped gametophyte has root like structure called rhizoids.
These rhizoids anchor the gametophyte to the substratum.
Mosunetuzumab is a T-cell reliant bispecific antibody that binds to CD3 and CD20 to trigger T-cell mediated B-cell death.
However, cytokine release syndrome, which has the potential to limit dose and efficacy, can result from powerful immune stimulation with T-cell focused treatments.
We created a novel mechanistic model of immune and antitumor responses to the T-cell bispecifics (mosunetuzumab and blinatumomab), taking into account the dynamics of B- and T-lymphocytes in circulation, lymphoid tissues, and tumors, in order to better understand the mechanisms underlying safety and efficacy as well as to explore safety mitigation strategies.
Using mosunetuzumab nonclinical and blinatumomab clinical data, the model was created and validated. The initial step-fractionated dose was projected to minimize systemic T-cell activation and cytokine release without impairing tumour response.
Simulations described the mechanisms underlying the observed cell and cytokine (IL6) dynamics. The Phase I clinical study for mosunetuzumab was changed to a step-fractionated treatment schedule as a result of these findings, allowing for the safer administration of greater dosages.
Learn more about cytokine brainly.com/question/14161482
#SPJ4
Answer:
(D) The Golgi apparatus cannot target the appropriate enzymes to the lysosome.
Explanation:
Enzymes are a type of protein build in ribosomes. The rough endoplasmic reticulum works with the golgi apparatus where proteins can be modified, sort and packed according to cell needs. Lysosomes are formed by budding of the Golgi apparatus.
