Disruption in the primary and quaternary structure.
Explanation:
The sickle cell anemia may be defined as the change in the amino acid at sixth position. Valine is present instead of glutamic acid in beta chain due to the point mutation in the nucleotide sequence.
The mutation causes the association of tetramers in the large fibers, this indicates that the quaternary structure of protein has been altered. This alteration must have occur due to the change in the amino acid sequence in the primary structure of the protein. Secondary or tertiary structure might or might not be altered in this mutation.
Thus, the correct answer is the alteration in the primary and quaternary structure.
The lining of the back of eye containing two types of photoreceptor cells - rods - sensitive to dim light and black and white - and cones - sensitive to colour. A small area called the fovea in the middle of the retina has many more cones than rods.
A hypothesis cannot be wrong, because it is an educated guess. You cannot prove a guess wrong. A guess is something you think, and there is no right or wrong answer to thoughts.
