1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
kow [346]
3 years ago
7

In sickle-cell disease, as a result of a single amino acid change, the mutant hemoglobin tetramers associate with each other and

assemble into large fibers. Based on this information alone, we can conclude that sickle-cell hemoglobin exhibits ________.
Biology
1 answer:
alekssr [168]3 years ago
6 0

Answer:

Disruption in the primary and quaternary structure.

Explanation:

The sickle cell anemia may be defined as the change in the amino acid at sixth position. Valine is present instead of glutamic acid in beta chain due to the point mutation in the nucleotide sequence.

The mutation causes the association of tetramers in the large fibers, this indicates that the quaternary structure of protein has been altered. This alteration must have occur due to the change in the amino acid sequence in the primary structure of the protein. Secondary or tertiary structure might or might not be altered in this mutation.

Thus, the correct answer is the alteration in the primary and quaternary structure.

You might be interested in
Which three organs produce enzymes that digest proteins ?
11111nata11111 [884]

1. Amylase, produced in the mouth. It helps break down large starch molecules into smaller sugar molecules.

2. Pepsin, produced in the stomach.

3. Trypsin, produced in the pancreas.

I'm probably wrong. Sorry.

4 0
3 years ago
¿Cuáles son los usos beneficiosos del fármaco que utiliza la comunidad médic?
Lelechka [254]

Answer:

In pharmacology, the term mechanism of action (MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor.

5 0
3 years ago
Suppose a species of bird called the red-crested warbler has a plumage length that is controlled by a single gene. The Plm allel
AleksAgata [21]

We are going to have different allele frequencies for the two populations

North American:

72 birds total => 144 alleles

72 - 55 birds = 17 short plume birds.

q^2 = (2*17) / 114 = 0.236

Freq(short plume allele) = q = 0.486

Freq(long plume allele) = p = 1 - q = 0.514

From this North American population we get

0.486 * 114 = 55 long plume alleles

0.514 * 114 = 59 short plume alleles

South American:

252 birds total => 504 alleles

252 - 75 birds = 177 short plume birds.

q^2 = (2*177) / 504 = 0.702

Freq(short plume allele) = q = 0.838

Freq(long plume allele) = p = 1 - q = 0.162

From this South American population we get

0.162 * 504 = 82 long plume alleles

0.838 * 504 = 422 short plume alleles

Blended population has

55 + 82 = 137 long plume alleles

59 + 422 = 481 short plume alleles

137 + 481 = 618 total alleles

p = 137/618 = 0.222

q = 481/618 = 0.778

The new population has the p and q from the blended population. The new population has 1000 individuals. The portion of long plumed will be homozygote long plumage + heterozygote, which is p^2 + 2pq, and you multiply that by the population size 1000 to get the final answer.

population size * (p^2 + 2pq) = 1000 * (0.222^2 + 2*0.222*0.778) = 395 birds (answer)

6 0
3 years ago
The activation of receptor tyrosine kinases is characterized by _____.
xxTIMURxx [149]

Answer:

dimerization and phosphorylation

Explanation:

Protein kinase receptors are simply saying receptors with associated kinases (usually tyrosine kinases).

Protein kinases are enzymes that have the ability to modulate other enzymes (or some other proteins) by adding the phosphate group. This is known as phosphorilation process. As a result of structural change, protein can change its activity (phosphorilation usually increase the activity).

Such receptors are involved in a many processes within an organism that are important for the cellular growth, differentiation, metabolism .

3 0
3 years ago
Which factor allows earth to hold onto liquid water?
vesna_86 [32]
I think the correct answer would be strong gravity. The factor that allows the earth to hold onto water would be the strong gravitational pull of the earth. In fact, it is what holds everything onto earth not only water. Hope this answers the question.
7 0
3 years ago
Read 2 more answers
Other questions:
  • If the sperm gamete that fertilizes an egg has a(n) _____ chromosome, it will form female offspring. X Y XY XX
    9·2 answers
  • melanin is a protein found in skin cells that protects from UV light damage caused by the sun. would the melanin gene be turned
    8·2 answers
  • Which biotic feature of a watershed helps prevent flooding?
    9·1 answer
  • 2 facts about mass *please make it small , i have to write it on a 1 by 1 inch block
    10·2 answers
  • Help me plz i really need to finish this
    9·2 answers
  • Which of these activities requires the use of a material resource?
    10·1 answer
  • How will wolf emigration affect a grassland ecosystem that supports rabbits, the wolf's primary prey?
    8·1 answer
  • Need help with the top question :p
    6·1 answer
  • What chemical compounds are in a sunflower?​
    13·1 answer
  • A population of birds from a West coast species and an East coast species migrate to the Midwest. They start breeding together a
    7·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!