DELTA-BLAST (select all that apply): Group of answer choices does not use a position-specific scoring matrix (PSSM) in calculati

Question

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DELTA-BLAST (select all that apply): Group of answer choices does not use a position-specific scoring matrix (PSSM) in calculati

ng a score. has the option of using PSI-BLAST iteratively following an initial search. uses a Conserved Domain Database as part of its search. is a powerful tool to look for related proteins with larger evolutionary divergence.

Biology

1 answer:

soldi70 [24.7K] · Answer 1 · 2022-01-30T20:33:03+03:00

Answer: the selections are on the explanations

Explanation:

BLAST is a commonly-used software package for comparing a query sequence to a database of known sequences.

Delta blast searches a database of pre-constructed PSSMs before searching a protein-sequence database, to yield better homology detection. It first uses RPS-BLAST to align a query sequence to conserved domains in CDD. DELTA-BLAST employs a subset of NCBI's (National Center for Biotechnology Information) Conserved Domain Database (CDD), which performs a sequence database search using a PSSM derived from the aligned domains.