Answer:
The correct answer is "both Cdc6 and Cdt1"
Explanation:
The replisome is a complex molecular system that allows for the replication of DNA in yeast. There are multiple genes that participate in the replisome function, however if a researcher finds out that a yeast strain fails to properly form replisomes it is very likely that the genes that might be mutated are both Cdc6 and Cdt1. Cdc6 and ORC are the genes that send the signal to the yeast to start the replisome formation, and Cdt1 is a DNA replication factor that if it is mutated it could cause that yeast is not able to form the replisome.
Answer:
The correct answer would be His mitochondria lack the transport protein that moves pyruvate across the outer mitochondrial membrane.
In cellular respiration, glycolysis takes place in the cytoplasm of the cell and converts glucose into 2 molecules of pyruvate. Pyruvate is then transported into the mitochondria for further oxidation.
It is transported into the mitochondria with the help of transport protein pyruvate translocase where it is decorboxylated to produce acetyl-CoA. This acetyl-CoA then enters the Krebs cycle to produce ATP (adenosine triphosphate) with the help of oxidative phosphorylation, electron transport chain and chemiosmosis.
In absence of this transport protein, the cell can not completely oxidize the glucose or carbohydrate. It switches to the metabolism of fats and amino acids in order to meet the energy demands of the cell.
There are so many examples for that in different areas, like biology experiment carried out in our lab recently.
Here's one link : https://www.creative-biogene.com/Services/ion-channel-cell-line-development.html
Proteins are an important class of molecules that carry out most of the work inside cells. The building blocks of proteins are smaller organic molecules called amino acids. Most organisms, including humans, use only 20 different amino acids to assemble the vast multitude of proteins needed to build and run a cell.
To build proteins, cells use a complex assembly of molecules called a ribosome. The ribosome assembles amino acids into the proper order and links them together via peptide bonds. This process, known as translation, creates a long string of amino acids called a polypeptide chain.
After the polypeptide chain is synthesized, it will sometimes undergo additional processing. For example, some proteins will have certain amino acids removed. Or extra molecules such as sugars or phosphates may be attached to some of the amino acids in a protein.