I believe that a Panamanian wildlife refuge can be found <span>in the heart of La Ciudad de Panama.
Panama City (= La Ciudad de Panama) is the capital of Panama and its largest city. If you are interested in seeing wildlife refuge of this city, it would be a good idea to go to the very center of the city because it is located there.
</span>
"<span>(c)the ability of citizens to vote" is the best answer but this is very misleading. A referendum is when the citizens vote directly on a specific issue of policy. It's not their ability to vote for mayors, legislators, etc.</span>