Needs to be transported to the mitochondria or the cytosol.
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</span>There are four stages of cellular respiration: glycolysis, pyruvate oxidation, Krebs cycle and Oxidative
phosphorylation. Glycolysis takes place in the cytosol of a cell,while the <span>pyruvate oxidation and the following steps take place </span> in the matrix of the mitochondria. If the enzyme is involved in cellular respiration, it need to be in one of these places.
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The substance must be able to alter its physical characteristic (for example, its color) in accordance to a change in pH. One example of this is litmus paper, which becomes red under acidic conditions and blue under basic conditions.