Temperature, sunlight, and water are examples of "abiotic factors'' or the second option. Abotic factor's are non-livings things that would affect organisms. For example temperature is non-living but can affect organisms, the same for sunlight, and water. It's not the first option because mineral sources are like mining shafts and others like coal. It's not biotic factors are all living things and temperature, sunlight, and water are non-living. Also food sources are food, for example gardens, and plantations etc...
Example of apoptosis is the death of RBC in three months duration. Too much RBC will lead to polycythemia. Which will work out the heart to pump. Too little RBC is called anemia if apoptosis is not regulated. Its symptom is fatigue.