Question 1:
<u>Answer</u>:
The "first line of defence" in innate immunity is "Physical and chemical barriers".
<u>Explanation</u>
"Physical and chemical barriers" is first line of defence includes that are ready to defend the living organism's body from infection at any time . These barriers include your skin, cilia, tears, urine flow, mucus, stomach acid, friendly bacteria and white blood cells . Skin acts as a mechanical barrier as it does not allows all the organism to pass through it unless the skin is cut or open. Similarly mouth eyes, and nose are also the ways through with the disease causing organism can enter the body. The micro-organisms that entered through these pathways are trapped either in saliva or mucus and swallowed and later either killed in the stomach or flushed out via the urine. If this first line of defence is broken or damaged, the second line of defence inside our body will be activated.
Question 2:
<u>Answer:</u>
Histamine kinins, and interleukins are examples of inflammatory mediators.
<u>Explanation</u>:
Inflammatory mediators are identified in inflammatory bowel disease IBD.These mediators play an vital role in the clinical and pathologic characteristics of the disorders. Cytokines, that are released by macrophages in due to antigenic stimuli, are binded different receptors and produce endocrine, autocrine and paracrine effects. Interleukins are a subset of a large group of 'cellular messenger molecules' called cytokines that modulates the cellular behaviour. Interleukins are not stored within cells like cytokines but they are released immediately, in response to a stimulus. Once an interleukin has been secreted, it moves to the target cell and binds to it through a receptor molecule on the surface of the cell . This interaction triggers a sequence of signals in the target cell that ultimately leads to the alteration in the behaviour of the cell.
C. to determine the compatibility of antibodies of donor and recipient.
Answer:
The growth factor receptors have a kinase domain while the Cytokines receptors do not contain a kinase domain as part of their structure.
Explanation:
The two are signaling molecules that control cell activities in some manners, such paracrine, endocrine and autocrine manners.
The receptor kinase domain can be specific for substrate sites in which phosphorylation occurs.
They’ve helped end/calm down pandemics and epidemics and allowed us to go out and start living our life again.
You don’t have to use this word for word just an idea
This is a question regarding how enzymes increase the rates of reactions. There are choices and the instructions is to check all that apply.
<span>1. They shift the reaction equilibrium towards the products. </span>
<span>2. They increase the concentration of the reactants. </span>
<span>3. They lower the activation energy of the reaction. </span>
<span>4. They decrease the free energy of a reaction. </span>
<span>5. They promote the formation of a transition state.
The correct answers in this question are "they lower the activation energy of the reaction" and "they promote the formation of a transition state". Enzymes do not necessarily shift the the reaction equilibrium to the products, as there are reversible enzymatic reactions that can reverse the pathway back to the substrates. They do not increase the concentration of the reactants as the concentration of the reactants is an independent variable in this process. They do not decrease the free energy of activation as this is a constant in every reaction depending on the substrates and the products.
Enzymes do, however, lower the activation energy of the reaction meaning it will take less energy and effort for the substrates to reach the activation energy to transform it to its transition state then to the products. With this said, enzymes promote the formation of a transition state.
Attached is a simplified image on how enzymes work. </span>