Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
Zinc. (Ans. B)
Explanation:
Trace minerals: Trace minerals are defined as the inorganic molecules which are necessary for the human body for the different functions.
Zinc function in human metabolism is defined as a cofactor for numerous enzymes. Zinc play a role as a catalyst in a broad range of reactions. It is involved in the metabolic pathway directly or indirectly with lipids, carbohydrates, proteins, energy metabolism, and they are also important for the cell division process.
They also need for tissue and growth repair, and for reproductive development also. It's also played a vital role in immune system such as wound healing or required for the function and structure of the skin.
Answer:
An explanation inspires new questions and the process of making new observations.
Explanation:
