Explanation:
The antidiuretic hormone (ADH), also known as arginine vasopressin (AVP), or argipressin, is a hormone produced in the hypothalamus that is stored and released through the neurohypophysis present in most mammals, including humans. Vasopressin is a peptide hormone that controls the reabsorption of water molecules by concentrating urine and reducing its volume, in the renal tubules, thus affecting tubular permeability. Vasopressin is released primarily in response to changes in serum osmolarity or blood volume increasing peripheral vascular resistance and in turn blood pressure. It receives its name because it plays a key role as a homeostatic regulator of fluids, glucose and salts in the blood.
It is a small hormone (oligopeptide) consisting of nine amino acids:
NH2-Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly-COOH
Vasopressin is a peptide hormone produced by the hypothalamus (supraoptic and paraventricular nuclei), but stored and secreted by the pituitary gland. Most are stored in the back of the pituitary gland (neurohypophysis) in order to be released into the blood. Vasopressin is in high concentrations in the locus coeruleus and in the black substance, which are catecholaminergic nuclei.
