Most models can't incorporate all the details of complex natural phenomena. For example, when measuring distances around the Earth it's convenient to model the Earth as a sphere, but this doesn't incorporate variations in distance because of mountain ranges, valleys and other topological features the traveler must traverse. Incorporating these additional details would make the model too complex for easy use. Since models must be simple enough that you can use them to make predictions, they often leave out some of the details.
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The conformation of molecules are based on probability. It fails to take into account the electronegativity of individual atoms. And it is ineffective in showing inorganic interactions with metals and such.
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coral reef is an underwater ecosystem characterized by reef-building corals. Reefs are formed of colonies of coral polyps held together by calcium carbonate. Most coral reefs are built from stony corals, whose polyps cluster in groups.
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Turner syndrome occurs among the females only because it has to do with the missing X chromosome. The effects of this syndrome is having a short height, ovary failure and heart defects. The female sex hormones, such as the estrogen and progesterone, are elevated.
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Knockout of the circadian clock protein per1 exacerbates hypertension and increases kidney injury in dahl salt-sensitive rats resulting in worsening of the SS hypertensive phenotype (1).
A circadian clock factor BMAL1, significantly found in kidneys, is known to affect blood pressure. Moreover, a diet high in salt is associated with immune cell infiltration in the kidney and consequently increases blood pressure. The BMAL1 factor is also responsible for expressing various genes. Mice, when treated with BMAL1 showed aging phenotypes like muscle weakness, changed gait, decreased mobility, inactivity, etc.
PER1 is a circadian clock transcription factor and is regulated by aldosterone. Nice on PER1 knock-out develops reduced sodium excretion with day and night differences. This is done in response to a high-salt diet.
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