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Anna [14]
3 years ago
5

Suggest a reason for the rather large energy excess available in the insertion of a deoxyribonucleotide into a growing DNA molec

ule. (About three times as much energy as is necessary is available in the reaction dNTP + DNAn → DNAn+1 + pyrophosphate.)
Biology
1 answer:
KonstantinChe [14]3 years ago
7 0
<h2>Favorable forward reaction </h2>

Explanation:

  • The very favorable forward reaction means that the reverse reaction is very unfavorable
  • This strong forward reaction driving energy effectively inhibits the depolymerization reaction DNAn + pyrophosphate → dNTP + DNAn-1
  • A response that both absorb heat and decreases entropy will be non-unconstrained (positive ∆G) at all temperatures. A few responses, in any case, have a blend of ideal and horrible properties (discharging heat yet diminishing entropy, or retaining heat yet expanding entropy). The ∆G and suddenness of these responses will rely upon the temperature

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Answer:

The correct answer would be - MMR would be hindered because both strands would be unmethylated and both would appear as new DNA strands and it would not be able to determine which strand has the error .

Explanation:

In gene expression or DNA replication, the enzyme responsible for the synthesis of DNA from nucleoside triphosphate causes errors sometimes such as mismatch base pair that result in a change in genetic makeup.

For MMR, the DNA template and the strand formed required easily to be differentiated. As the newly synthesized strand is unmethylated and the DNA template strand is methylated results in DNA remain hemimethylated for a very short period.

After MMR, DNA adenine methylase enzyme that transfers a methyl group to the adenine of the sequence 5'-GATC-3' daughter strand formed.

Mutated DAM or DNA adenine methylase will not be able to transfer methyl group which leaves both template and daughter strands unmethylated and mismatch repair would be hindered as it will not be able to identify.

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