Arrange the following events for the synthesis of RNA in the correct order: Nucleophilic attack of the 3′ OH group of the first
nucleotide at the α-phosphate group of the second nucleotide 5′ triphosphate occurs. Template specific rNTPs are bound. Several DNA bases are unwound, forming a stable complex. Polymerase finds a promoter region. A Mg+2-dependent isomerization of DNA takes place.
The process of syhthesis of protein is called trancription.
The proces sf transcription begin with the binding of RNA polymerase enzyme with a sequence of DNA called the promoter.
RNA polymerase allows the unwinding of DNA bases forming a stable complex.
In the next step, a Mg2+-dependent isomerization occurs, that produces a modified form of the open- promoter complex.
RNA polymerase has one nucleoside triphosphate binding site which helps during elongation and binds any of the four common ribonucleoside triphosphates (rNTPs).
Then a nucleophilic attack of the 3' hydroxyl (OH) present at the first nucleotide on the a - phosphorus gorup of the second nucleotide 5' triphosphate occurs that forms the first phosphodiester bond.
