Answer:
DNA vaccines consist of DNA vectors or plasmids (small double-stranded DNA rings originally derived from bacteria, but unable to cause infection) into which the genes encoding one or more immunizing proteins of the infectious agent have been inserted causing the disease to be prevented.
Explanation:
Vectors are the functional unit of naked DNA vaccines. Genes that encode the proteins of interest and are of bacterial origin are inserted into these vectors. Bacterial plasmids are circular DNA molecules that self-replicate extrachromosomally in bacteria. The genes encoded in these plasmids are under the control of promoters, almost always of viral origin. When a plasmid is introduced into the cell it translocates to the nucleus, where transcription of the transgene begins; the transcripts are then taken to the cytoplasm and translated there. The newly synthesized proteins are degraded in the proteasome to 8-10 amino acid peptides, which are transported to the endoplasmic reticulum. Peptides of high affinity with their respective MHC I molecule stabilize and enter the secretory pathway, thus reaching the cell surface, where they are coupled with the T-lymphocyte receptor (TcR) present on the surface of T lymphocytes cytotoxic drugs (CD8 +) to induce their activation.
Answer:
the Coriolis effect
Explanation:
the earths rotation causes wind also known as the coriolis effect
Answer:
Antibodies
Explanation:
Bordetella pertussis is an obligate human pathogen and is the etiological agent of whooping cough. It is known to be an opportunistic organism.
The pathogenic mechanism of Bordetella pertussis is also known as virulence factor. These virulence factors are known to include adhesins such as filamentous haemagglutinin, fimbriae and pertactin, which allow B. pertussis to bind to ciliated epithelial cells in the upper respiratory tract.
It is known to be the agent of whooping cough, a highly contagious respiratory disease, dramatic for infants and also for elderly and pregnant women.
In this case, the antibodies will be the response that is uniquely directed against the organism. It is said earlier that this organism is an opportunistic one, this means that it causes infection when the immunity is down. So, when the immunity is empowered , it will definitely fight against the organism
