An issue related to long term heroin use is deterioration of the brain's white matter, which affects decision-making abilities, the regulation of behaviour or how we respond to stressful situations. This is caused because long term heroin use affects the physiology and physical structure of the brain, and causes imbalances in the neuronal and hormonal systems. These effects are not easily reversed because the use of heroine creates physiological dependence on the drug.
The British government tightened control by not allowing the settlers to move west So they were kept in a smaller place. Also the British government made the quartering act that made the colonists house redcoats in their homes.
